Description

5-Methyl-L-Norleucine Orlistat Analogue is a specialized synthetic amino acid derivative designed as a structural analog of Orlistat, a well-known lipase inhibitor. This compound is engineered for advanced pharmaceutical research, particularly in the study of metabolic pathways and the development of novel therapeutic agents targeting obesity and related metabolic disorders. It serves as a critical building block and reference standard for medicinal chemists and research scientists in the pharmaceutical and biotechnology sectors, enabling precise structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel lipase inhibitors and other bioactive molecules targeting metabolic diseases.
• Medicinal Chemistry Research: Used extensively in Structure-Activity Relationship (SAR) studies to optimize the potency and selectivity of drug candidates.
• Biochemical Research: Serves as a tool compound for investigating enzyme inhibition mechanisms, particularly against gastrointestinal lipases.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis (HPLC, LC-MS).
• Peptide Synthesis: Utilized as a modified, non-proteinogenic amino acid building block for creating specialized peptide sequences with unique properties.

Basic Information

Product Name	5-Methyl-L-Norleucine Orlistat Analogue
CAS No.	1356847-30-7
Molecular Formula	C7H15NO2
Molecular Weight	145.20 g/mol
Synonyms	(2S)-2-Amino-5-methylhexanoic acid; L-5-Methylnorleucine; (S)-2-Amino-5-methylcaproic acid; Orlistat Impurity; Orlistat Related Compound; 5-Methyl-L-2-aminocaproic acid; (S)-5-Methyl-2-aminocaproic acid
EINECS	Contact for details

Quality Control

Every batch of our 5-Methyl-L-Norleucine Orlistat Analogue is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and compliance with your research or development protocols. Our standard quality commitment includes identity confirmation by spectroscopic methods (IR, NMR), purity assessment by HPLC, and chiral purity verification. A detailed Certificate of Analysis (COA) is supplied with each shipment, and custom specifications can be developed to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.