Description

Aspartame-D3 is a stable isotope-labeled analog of the widely used artificial sweetener aspartame, where three hydrogen atoms are replaced by deuterium. This precise labeling makes it an indispensable internal standard for accurate quantification and metabolic pathway analysis in scientific research. It is primarily required by analytical laboratories, pharmaceutical R&D departments, and food science researchers conducting high-precision mass spectrometry studies.

Application

• Internal Standard for LC-MS/MS and GC-MS analysis of aspartame in food, beverage, and biological samples.
• Metabolic tracer studies to investigate the pharmacokinetics and biotransformation pathways of aspartame.
• Quality control and method validation in regulatory testing and compliance laboratories.
• Use in stable isotope dilution assays (SIDA) for achieving superior accuracy in quantitative analysis.
• Research tool in nutritional science and toxicology studies related to artificial sweeteners.
• Calibration standard for ensuring data integrity in high-throughput analytical environments.

Basic Information

Product Name	Aspartame-D3
CAS No.	1356841-28-5
Molecular Formula	C14H15D3N2O5
Molecular Weight	297.31 g/mol
Synonyms	L-Aspartic acid, N-L-α-aspartyl-L-phenylalanine-3,3,3-d3 methyl ester; N-L-α-Aspartyl-L-phenylalanine-3,3,3-d3 methyl ester; Aspartame-d3; APM-d3; 3,3,3-Trideutero-N-(L-α-aspartyl)-L-phenylalanine 1-methyl ester; Isotopically Labeled Aspartame; Deuterated Aspartame; NutraSweet-d3
EINECS	Contact for details

Quality Control

Our Aspartame-D3 is produced under strict quality management systems to ensure the highest isotopic and chemical purity for critical research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (D-atom %), chemical purity by HPLC, and identification data. We support compliance with GMP and ISO guidelines for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-atom %)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.