Description

Methyl 2-Cyano-5-Fluoronicotinate is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which enables the introduction of both cyano and fluoro substituents onto a nicotinate core, facilitating the development of novel compounds with targeted properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluoronicotinate moiety can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for the synthesis of specialized ligands, organic semiconductors, and liquid crystal materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and contract research organizations (CROs) requiring specific fluorinated heterocycles.

Basic Information

Product Name	Methyl 2-Cyano-5-Fluoronicotinate
CAS No.	1356110-37-6
Molecular Formula	C8H5FN2O2
Molecular Weight	180.14 g/mol
Synonyms	5-Fluoro-2-cyanonicotinic acid methyl ester; Methyl 5-fluoro-2-cyanopyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 2-cyano-5-fluoro-, methyl ester; 2-Cyano-5-fluoronicotinic acid methyl ester; Methyl 5-fluoro-2-cyano-3-pyridinecarboxylate
EINECS	Contact for details

Quality Control

Our Methyl 2-Cyano-5-Fluoronicotinate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.