Description

n-Benzyloxycarbonyl-o-Benzoyl Aspartame-D5 is a deuterated derivative of a protected aspartame intermediate, specifically designed for research and analytical applications. This compound is of significant value as a high-purity internal standard for mass spectrometry, enabling precise quantification and metabolic studies of aspartame and related peptides. It is primarily needed by analytical chemists and researchers in the pharmaceutical, food science, and regulatory testing industries who require stable isotope-labeled references for method development and validation.

Application

• Internal Standard for LC-MS/MS Analysis: Used as a deuterated internal standard for the accurate quantification of aspartame and its metabolites in complex biological and food matrices.
• Pharmaceutical Research: Facilitates metabolic pathway studies and pharmacokinetic profiling of peptide-based compounds and sweeteners.
• Food & Beverage Testing: Enables high-sensitivity detection and confirmation of aspartame levels in products for quality control and regulatory compliance.
• Method Development & Validation: Serves as a critical reference material for developing robust analytical methods in contract research organizations (CROs) and testing laboratories.
• Stable Isotope Labeling Studies: Employed in research involving isotope dilution techniques to ensure data accuracy and reliability.

Basic Information

Product Name	n-Benzyloxycarbonyl-o-Benzoyl Aspartame-D5
CAS No.	1356011-62-5
Molecular Formula	C26H20D5N2O8
Molecular Weight	~496.5 g/mol
Synonyms	Z-Aspartame(OBzl)-D5; N-CBZ-O-Benzoyl Aspartame-D5; Aspartame-D5, N-benzyloxycarbonyl-O-benzoyl; L-Aspartic acid, N-[(benzyloxy)carbonyl]-4-[(2,3,4,5,6-pentadeuteriophenyl)methyl] ester, 1-L-phenylalanine 1-methyl ester; Deuterated Z-Aspartame(OBzl); Deuterated Protected Aspartame Intermediate; (3S)-3-[[(2S)-1-Methoxy-1-oxo-3-phenylpropan-2-yl]carbamoyl]-4-[(2,3,4,5,6-pentadeuteriophenyl)methoxy]-4-oxobutanoic acid benzyl ester
EINECS	Contact for details

Quality Control

Our n-Benzyloxycarbonyl-o-Benzoyl Aspartame-D5 is manufactured under strict quality systems to ensure high chemical purity and isotopic enrichment suitable for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as chemical purity (by HPLC), isotopic purity (D-enrichment), and identification. We adhere to industry best practices for reference material production, ensuring reliability and consistency for your critical research and testing needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.