Description

Aldose Reductase-In-1 CAS NO 1355612-71-3 is a potent and selective small molecule inhibitor of the aldose reductase enzyme, a key target in metabolic pathway research. This compound is critical for investigating the polyol pathway and its role in diabetic complications, offering high specificity for reliable experimental results. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on metabolic disease, neuropathy, and ophthalmic research.

Application

• Biochemical Research: Used as a selective tool compound to study the inhibition kinetics and mechanism of aldose reductase (ALR2) in vitro.
• Drug Discovery & Development: Serves as a reference standard or lead compound in high-throughput screening campaigns for novel therapeutics targeting diabetic complications.
• Academic Studies: Facilitates research into the polyol pathway's role in diabetic neuropathy, retinopathy, nephropathy, and cataract formation.
• Target Validation: Employed in cellular and animal models to validate aldose reductase as a therapeutic target for metabolic disorders.
• Enzyme Assay Development: Acts as a control inhibitor in the development and optimization of enzymatic assays for aldose reductase activity.

Basic Information

Product Name	Aldose Reductase-In-1
CAS No.	1355612-71-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Aldose Reductase Inhibitor-1; AR Inhibitor-1; ALR2 Inhibitor-1; (Chemical name to be confirmed); (IUPAC name to be confirmed); (Abbreviation to be confirmed); (Trade name to be confirmed)
EINECS	Contact for details

Quality Control

Our Aldose Reductase-In-1 is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including purity verification by HPLC and structural confirmation. A detailed Certificate of Analysis (COA) containing identity, purity, and impurity profile is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term use, the product may be stored at 2-8°C. The container should be allowed to reach room temperature before opening to prevent moisture condensation. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.