Description

3,5,6-Trifluoro-4-Hydroxypyridine-2-Carboxylic Acid is a high-value fluorinated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a carboxylic acid and multiple fluorine atoms, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in areas like kinase inhibitors and antibacterial agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where fluorine substitution enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic electronic materials.
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for studying biological mechanisms.

Basic Information

Product Name	3,5,6-Trifluoro-4-Hydroxypyridine-2-Carboxylic Acid
CAS No.	1353101-92-4
Molecular Formula	C6H2F3NO3
Molecular Weight	193.08 g/mol
Synonyms	4-Hydroxy-3,5,6-trifluoropyridine-2-carboxylic acid; 2-Carboxy-3,5,6-trifluoro-4-hydroxypyridine; 3,5,6-Trifluoro-4-hydroxypicolinic acid; 3,5,6-Trifluoro-4-pyridinol-2-carboxylic acid; TFHPC Acid; 1353101-92-4; 4-Hydroxy-3,5,6-trifluoro-2-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of 3,5,6-Trifluoro-4-Hydroxypyridine-2-Carboxylic Acid adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We are committed to meeting the exacting requirements of cGMP and ISO 9001 standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.