Description

4-Fluoropyrazolo[1,5-A]Pyridine-3-Carboxylic Acid is a high-purity fluorinated heterocyclic building block of significant importance in modern pharmaceutical and agrochemical research. Its core value lies in its unique molecular scaffold, which serves as a versatile intermediate for the synthesis of novel active compounds. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to incorporate a fluorinated pyrazolopyridine moiety into their target molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Chemical Biology & Medicinal Chemistry: Employed as a probe or scaffold in hit-to-lead optimization and structure-activity relationship (SAR) studies.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials or metal-organic frameworks (MOFs) due to its rigid, heteroaromatic structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects requiring this specific fluorinated heterocycle.

Basic Information

Product Name	4-Fluoropyrazolo[1,5-A]Pyridine-3-Carboxylic Acid
CAS No.	1352625-33-2
Molecular Formula	C8H5FN2O2
Molecular Weight	180.14 g/mol
Synonyms	4-Fluoropyrazolo[1,5-a]pyridine-3-carboxylic acid; 4-Fluoro-1H-pyrazolo[1,5-a]pyridine-3-carboxylic acid; 4-Fluoro-pyrazolo[1,5-a]pyridine-3-carboxylic acid; 3-Carboxy-4-fluoropyrazolo[1,5-a]pyridine; 4-Fluoro-3-pyrazolo[1,5-a]pyridinecarboxylic acid; 1352625-33-2; 4-Fluoropyrazolopyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoropyrazolo[1,5-A]Pyridine-3-Carboxylic Acid is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled accordingly. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.