Description

2-Quinolinecarboxaldehyde, 7,8-Difluoro- is a high-value, fluorinated quinoline derivative serving as a critical building block in advanced organic synthesis. Its core value lies in its unique molecular architecture, which introduces both an aldehyde functional group and strategic fluorine atoms onto the quinoline scaffold, enabling precise modifications for developing novel compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in developing kinase inhibitors, antimicrobial agents, and other biologically active molecules.
• Agrochemical Research: Used to construct advanced intermediates for new-generation herbicides, fungicides, and pesticides, leveraging the bioactivity-enhancing properties of fluorine.
• Material Science: Serves as a building block for creating specialized ligands, organic semiconductors, and fluorinated polymers with tailored electronic or optical properties.
• Chemical Synthesis: The reactive aldehyde group facilitates further transformations such as condensation, reductive amination, and heterocycle formation, making it a versatile synthon.
• Fluorine Chemistry Studies: An important compound for academic and industrial research focused on understanding structure-activity relationships (SAR) in fluorinated heterocycles.

Basic Information

Product Name	2-Quinolinecarboxaldehyde, 7,8-Difluoro-
CAS No.	1351517-03-7
Molecular Formula	C₁₀H₅F₂NO
Molecular Weight	193.15 g/mol
Synonyms	7,8-Difluoroquinoline-2-carboxaldehyde; 7,8-Difluoro-2-formylquinoline; 2-Formyl-7,8-difluoroquinoline; 7,8-Difluoro-2-quinolinecarbaldehyde; 7,8-Difluoroquinoline-2-carbaldehyde; 1351517-03-7; 7,8-Difluoro-2-quinolinecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 2-Quinolinecarboxaldehyde, 7,8-Difluoro- is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC-MS, and NMR, for comprehensive characterization and impurity profiling. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and conformance to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere if prolonged exposure is anticipated to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.