Description

2,6-Dimethyl-2',4'-Difluorobiphenyl-4-Carboxaldehyde is a high-purity, multi-functional biphenyl derivative featuring a reactive aldehyde group and strategically placed fluorine and methyl substituents. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern organic synthesis. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used as a building block for developing novel herbicides, fungicides, and insecticides, leveraging the stability imparted by the fluorine atoms.
• Liquid Crystal & OLED Materials: Serves as a core structure in the development of advanced electronic materials for displays and lighting due to its rigid biphenyl core and modifiable functional groups.
• Ligand & Catalyst Development: Employed in the design of specialized ligands for transition metal catalysis and asymmetric synthesis.
• Polymer & Resin Modifier: Acts as a monomer or cross-linking agent to introduce specific properties like thermal stability or hydrophobicity into polymer chains.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and aldehyde functionalization.

Basic Information

Item	Details
Product Name	2,6-Dimethyl-2',4'-Difluorobiphenyl-4-Carboxaldehyde
CAS No.	1350760-27-8
Molecular Formula	C₁₅H₁₂F₂O
Molecular Weight	246.25 g/mol
Synonyms	4-Formyl-2,6-dimethyl-2',4'-difluorobiphenyl; 2',4'-Difluoro-2,6-dimethylbiphenyl-4-carboxaldehyde; 2,6-Dimethyl-2',4'-difluoro[1,1'-biphenyl]-4-carboxaldehyde; 2,6-Dimethyl-2',4'-difluorobiphenyl-4-aldehyde; (2',4'-Difluoro-2,6-dimethyl-[1,1'-biphenyl]-4-yl)methanal; Biphenyl-4-carboxaldehyde, 2',4'-difluoro-2,6-dimethyl-; CAS 1350760-27-8
EINECS	Contact for details

Quality Control

Every batch of 2,6-Dimethyl-2',4'-Difluorobiphenyl-4-Carboxaldehyde is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and structural integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.