Description

2,6-Dimethyl-4'-Fluorobiphenyl-4-Carboxaldehyde is a high-purity, specialized biphenyl derivative featuring a formyl group and fluorine substitution. This compound serves as a critical advanced pharmaceutical intermediate and versatile building block in modern organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the biphenyl scaffold for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors for OLEDs, due to its conjugated biphenyl core.
• Chemical Biology Probes: Useful for synthesizing fluorescent tags or molecular probes for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	2,6-Dimethyl-4'-Fluorobiphenyl-4-Carboxaldehyde
CAS No.	1350760-25-6
Molecular Formula	C15H13FO
Molecular Weight	228.26 g/mol
Synonyms	4'-Fluoro-2,6-dimethylbiphenyl-4-carboxaldehyde; 4-Formyl-4'-fluoro-2,6-dimethylbiphenyl; 2,6-Dimethyl-4'-(fluorobiphenyl)-4-carbaldehyde; 4'-Fluoro-2,6-dimethyl-[1,1'-biphenyl]-4-carbaldehyde; (4'-Fluoro-2,6-dimethyl-[1,1'-biphenyl]-4-yl)methanal
EINECS	Contact for details

Quality Control

Every batch of 2,6-Dimethyl-4'-Fluorobiphenyl-4-Carboxaldehyde is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical R&D and scale-up processes. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are available upon request. Our quality commitment supports compliance with cGMP and ICH Q7 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.