Description

5-(1H-Pyrazol-5-Yl)-2-Furansulfonyl Chloride is a high-value sulfonyl chloride derivative, a key synthetic intermediate in modern organic chemistry. Its primary commercial value lies in its role as a versatile electrophilic building block for constructing complex heterocyclic systems. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, especially those targeting enzyme inhibition or receptor modulation.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science Research: Serves as a building block for creating advanced polymers or functional organic materials with specific electronic or photophysical properties.
• Chemical Biology Probes: Employed in the synthesis of activity-based probes (ABPs) or affinity labels for studying biological processes and target identification.
• Cross-Coupling Reactions: Acts as an electrophilic partner in various metal-catalyzed cross-coupling reactions to form carbon-sulfur or carbon-nitrogen bonds.
• Sulfonamide Library Synthesis: A key reagent for the parallel or combinatorial synthesis of diverse sulfonamide libraries for high-throughput screening.

Basic Information

Product Name	5-(1H-Pyrazol-5-Yl)-2-Furansulfonyl Chloride
CAS No.	1350521-74-2
Molecular Formula	C7H5ClN2O3S
Molecular Weight	232.64 g/mol
Synonyms	5-(1H-Pyrazol-5-yl)furan-2-sulfonyl chloride; 2-Furansulfonyl chloride, 5-(1H-pyrazol-5-yl)-; 5-(1H-Pyrazol-5-yl)-2-furansulfonyl chloride; 5-(1H-Pyrazol-5-yl)furan-2-sulfonylchloride; 5-(1H-Pyrazol-5-yl)thiophene-2-sulfonyl chloride (common misnomer); 5-Pyrazol-5-ylfuran-2-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our production of 5-(1H-Pyrazol-5-Yl)-2-Furansulfonyl Chloride adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the material should be handled under an inert atmosphere (e.g., nitrogen or argon) and stored with appropriate desiccants. Recommended long-term storage temperature is between 2°C and 8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.