Description

Alfuzosin-D7 is a deuterium-labeled analog of the α-1 adrenergic receptor antagonist Alfuzosin, serving as a critical internal standard for precise quantitative analysis. This high-purity stable isotope-labeled compound is essential for ensuring accuracy and reliability in pharmacokinetic and metabolism studies. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical testing facilities engaged in bioanalytical method development and drug metabolism research using LC-MS/MS or GC-MS techniques.

Application

• Internal Standard for LC-MS/MS and GC-MS bioanalysis of Alfuzosin in biological matrices (plasma, serum, urine).
• Quantitative reference material in pharmacokinetic (PK) and pharmacodynamic (PD) studies.
• Critical component in the development and validation of GLP/GCP-compliant bioanalytical methods.
• Use in drug metabolism and excretion studies to track the parent drug.
• Calibration standard for ensuring accuracy in high-throughput clinical testing.
• Research tool in comparative bioavailability and bioequivalence studies.
• Quality control standard for the analysis of Alfuzosin in pharmaceutical formulations.

Basic Information

Product Name	Alfuzosin-D7
CAS No.	1346746-88-0
Molecular Formula	C₁₉H₂₀D₇N₅O₄
Molecular Weight	~ 398.48 g/mol
Synonyms	Alfuzosin (phenyl-d7); Alfuzosin-d7; N-[3-[(4-Amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-2-furancarboxamide-d7; (RS)-N-[3-[(4-Amino-6,7-dimethoxyquinazolin-2-yl)-methylamino]propyl]tetrahydrofuran-2-carboxamide-d7; Deuterated Alfuzosin; Alfuzosin Internal Standard
EINECS	Contact for details

Quality Control

Our Alfuzosin-D7 is manufactured under strict quality control protocols to ensure the high chemical and isotopic purity required for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing results for identity, assay, isotopic enrichment, and purity by HPLC. We adhere to relevant industry standards for stable isotope-labeled compounds to guarantee reliable and reproducible performance as an internal standard.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Chemical Purity	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.