Description

Methyl 5-(2,4-Difluorophenyl)Nicotinate is a high-value pharmaceutical intermediate and fine chemical building block. This compound is critical for the synthesis of advanced active pharmaceutical ingredients (APIs) and other complex organic molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and functional materials. Its precise structure offers a versatile platform for further chemical modifications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the difluorophenyl moiety for enhanced biological activity and stability.
• Chemical Research & Development: Serves as a versatile precursor in organic synthesis for creating complex heterocyclic compounds and functionalized nicotinate derivatives.
• Material Science: Potential intermediate for the synthesis of specialty polymers, liquid crystals, or organic electronic materials requiring specific fluorinated aromatic units.

Basic Information

Product Name	Methyl 5-(2,4-Difluorophenyl)Nicotinate
CAS No.	1346691-66-4
Molecular Formula	C13H9F2NO2
Molecular Weight	249.21 g/mol
Synonyms	5-(2,4-Difluorophenyl)nicotinic acid methyl ester; Methyl 5-(2,4-difluorophenyl)pyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 5-(2,4-difluorophenyl)-, methyl ester; Nicotinic acid, 5-(2,4-difluorophenyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 5-(2,4-Difluorophenyl)Nicotinate adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.