Description

Phenelzine-D4 Sulfate is a deuterated isotopologue of the monoamine oxidase inhibitor (MAOI) phenelzine sulfate, specifically labeled with four deuterium atoms. This stable isotope-labeled compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring high analytical accuracy and reproducibility. It is primarily required by pharmaceutical research and development laboratories, contract research organizations (CROs), and analytical testing facilities engaged in pharmacokinetic studies, drug metabolism research, and bioanalytical method development for MAOI drugs.

Application

• Internal Standard for LC-MS/MS: Critical for the precise quantification of phenelzine and its metabolites in complex biological matrices like plasma, serum, and urine.
• Drug Metabolism and Pharmacokinetics (DMPK): Used in absorption, distribution, metabolism, and excretion (ADME) studies to track the parent drug.
• Bioanalytical Method Development and Validation: Serves as a reference compound to establish robust, sensitive, and specific analytical assays.
• Clinical Research and Therapeutic Drug Monitoring (TDM): Enables accurate measurement of drug concentrations in patient samples for dose optimization.
• Pharmaceutical Impurity Profiling: Can be utilized in stability studies and impurity identification pathways.
• Forensic and Toxicology Analysis: Supports the accurate identification and quantification of phenelzine in forensic investigations.

Basic Information

Product Name	Phenelzine-D4 Sulfate
CAS No.	1346605-03-5
Molecular Formula	C8D4H8N2 • H2SO4
Molecular Weight	Contact for details
Synonyms	(±)-2-Phenylethylhydrazine-d4 Sulfate; Phenelzine-d4 Hemisulfate Salt; 2-(Phenyl-d4)ethylhydrazine Sulfate; Nardil-d4 (labeled analogue); β-Phenylethylhydrazine-d4 Sulfate; 1-Amino-2-phenylethane-d4 Hydrazine Sulfate; Benzeneethanamine-d4, 2-hydrazinyl-, sulfate (1:1)
EINECS	Contact for details

Quality Control

Our Phenelzine-D4 Sulfate is manufactured under strict quality systems to ensure the high chemical purity and isotopic enrichment required for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as assay (by HPLC), isotopic purity (by MS), and identification (by NMR/IR). We adhere to relevant industry standards for stable isotope-labeled compounds, and custom specifications for GMP or research-grade materials are available.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (MS)	≥98 atom % D
Chemical Purity (Titration)	Contact for details
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.