Description

2-[4-(1,1-Dicarboethoxy)Benzyl]-2-Methyl Malonic Acid-D3 is a high-purity, deuterium-labeled chemical intermediate of significant importance in advanced research and development. This compound is specifically valued for its role as a stable isotope-labeled building block, enabling precise metabolic and pharmacokinetic studies. It is primarily needed by pharmaceutical R&D laboratories, agrochemical innovators, and analytical chemistry facilities focused on developing and tracing novel active compounds.

Application

• As a deuterium-labeled synthetic intermediate in the research and development of new pharmaceutical candidates.
• For use in metabolic pathway studies and pharmacokinetic (PK) research using mass spectrometry (MS) and nuclear magnetic resonance (NMR) techniques.
• In the synthesis of isotope-labeled standards for accurate quantitative analysis in bioanalytical assays.
• As a specialized building block in agrochemical research for developing novel crop protection agents.
• For mechanistic studies in organic and medicinal chemistry, leveraging the kinetic isotope effect (KIE).
• In the production of advanced materials and fine chemicals where isotopic purity is a critical parameter.

Basic Information

Product Name	2-[4-(1,1-Dicarboethoxy)Benzyl]-2-Methyl Malonic Acid-D3
CAS No.	1346604-53-2
Molecular Formula	C19H23D3O8
Molecular Weight	385.42 g/mol (approx.)
Synonyms	2-[4-(1,1-Diethoxycarbonyl)benzyl]-2-methylpropanedioic acid-d3; 2-Methyl-2-[4-(1,1-diethoxycarbonyl)benzyl]malonic Acid-d3; Deuterated 2-[4-(1,1-Dicarboethoxy)Benzyl]-2-Methyl Malonic Acid; 2-(4-(1,1-Bis(ethoxycarbonyl))benzyl)-2-methylmalonic Acid-d3; (2-Methyl-2-(4-(1,1-di(ethoxycarbonyl))phenyl)methyl)propanedioic Acid-d3; D3-labeled Malonic Acid Derivative; Isotope-labeled Diethyl Benzylmalonate Derivative
EINECS	Contact for details

Quality Control

Every batch of 2-[4-(1,1-Dicarboethoxy)Benzyl]-2-Methyl Malonic Acid-D3 is produced and tested under strict quality management protocols to ensure high isotopic and chemical purity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing parameters such as isotopic purity (D-enrichment), chemical purity (HPLC), and identity confirmation (NMR, MS) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.