Description

Ponazuril-D3 is a deuterated analog of the triazine-based antiprotozoal agent Ponazuril, specifically designed for use as an internal standard in analytical chemistry. This high-purity, isotopically labeled compound is essential for ensuring the accuracy and reliability of quantitative analysis, particularly in pharmacokinetic and metabolic studies. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical testing facilities engaged in method development and quality control for veterinary and human health products.

Application

• Internal Standard for LC-MS/MS and GC-MS analysis of Ponazuril and its metabolites.
• Quantitative bioanalysis in pharmacokinetic (PK) and toxicokinetic (TK) studies.
• Method development and validation for regulatory submissions in veterinary medicine.
• Stability-indicating assay development for drug substance and product testing.
• Metabolite identification and profiling research in preclinical models.
• Quality control and assurance in the manufacturing of active pharmaceutical ingredients (APIs).

Basic Information

Item	Detail
Product Name	Ponazuril-D3
CAS No.	1346602-48-9
Molecular Formula	C18H11D3F3N3O4S
Molecular Weight	416.38 g/mol
Synonyms	1-Methyl-3-[3-methyl-4-[4-(trifluoromethoxy)phenoxy]phenyl]-5-(propyl-d7)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione; Deuterated Ponazuril; Ponazuril-d3; Toltrazuril sulfone-d3; [D3]-Ponazuril; Marquis-d3 (common research name); Isotopic internal standard for Ponazuril
EINECS	Contact for details

Quality Control

Our Ponazuril-D3 is manufactured under strict quality management systems to ensure the highest standards of isotopic purity and chemical integrity. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, HPLC, and mass spectrometry, to confirm identity, isotopic enrichment, and chemical purity. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the material should be handled in a low-humidity environment and the container kept sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 99.0 atom % D
Chemical Purity (by HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.