Description

5,6-Diamino-4-Thiouracil-13C2 is a stable isotope-labeled derivative of a key heterocyclic thiouracil scaffold, specifically labeled with carbon-13 at two positions. This compound is of critical importance for research and development in analytical chemistry and pharmaceutical sciences, where precise molecular tracking is required. It is primarily needed by scientists and manufacturers in the fields of isotope dilution mass spectrometry, metabolic pathway studies, and as a labeled precursor for the synthesis of more complex bioactive molecules.

Application

• Internal Standard for LC-MS/MS: Serves as a crucial, high-purity internal standard for the accurate quantification of thiouracil analogs in complex biological matrices via isotope dilution mass spectrometry.
• Metabolic Research: Used as a labeled tracer to study the absorption, distribution, metabolism, and excretion (ADME) profiles of thiouracil-based compounds in pharmacokinetic studies.
• Pharmaceutical Reference Standard: Employed as a certified reference material (CRM) for method validation, quality control, and regulatory compliance in drug development and manufacturing.
• Precursor for Labeled APIs: Acts as a key synthetic building block for the preparation of carbon-13 labeled active pharmaceutical ingredients (APIs) or advanced intermediates.
• Biochemical Pathway Analysis: Facilitates research into nucleotide metabolism and related enzymatic processes where the thiouracil moiety is involved.

Basic Information

Product Name	5,6-Diamino-4-Thiouracil-13C2
CAS No.	1346601-57-7
Molecular Formula	C413C2H6N4OS
Molecular Weight	~174.16 g/mol (for 13C2 labeled form)
Synonyms	4-Thio-5,6-diaminouracil-13C2; 5,6-Diamino-2-mercapto-4-pyrimidinol-13C2; 5,6-Diamino-2-thioxo-1,2-dihydropyrimidin-4(3H)-one-13C2; 13C2-Labeled 5,6-Diamino-4-thiouracil; 5,6-Diamino-2-thio-4-hydroxypyrimidine-13C2; Isotopically labeled 5,6-diamino-4-thiouracil; [13C2]-5,6-Diamino-4-thiouracil
EINECS	Contact for details

Quality Control

Our 5,6-Diamino-4-Thiouracil-13C2 is manufactured under controlled conditions to ensure exceptional isotopic and chemical purity, meeting the stringent requirements of analytical and research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment (atom % 13C), chemical purity by HPLC, and identification by spectroscopic methods. We adhere to rigorous in-house quality standards to guarantee batch-to-batch consistency and reliability for your critical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Enrichment	≥ 99 atom % 13C (at labeled positions)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.