Description

Rac Desisopropyl Tolterodine-D7 CAS NO 1346600-20-1 is a deuterium-labeled isotopologue of a key tolterodine intermediate. This compound is of significant value as a stable isotope-labeled internal standard in quantitative bioanalytical methods, ensuring precise and accurate measurement. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical service providers engaged in pharmacokinetic studies, drug metabolism research, and high-sensitivity LC-MS/MS method development.

Application

• Internal standard for the quantification of tolterodine and its metabolites in biological matrices (e.g., plasma, urine) via LC-MS/MS.
• Critical reagent in pharmaceutical research for conducting Absorption, Distribution, Metabolism, and Excretion (ADME) studies.
• Use in method development and validation to meet regulatory standards for bioanalytical assays (e.g., FDA, EMA guidelines).
• Supporting clinical trial sample analysis to ensure data integrity and reliability.
• Application in forensic and doping control analysis for precise detection of related compounds.
• Tool for mechanistic studies in medicinal chemistry to understand metabolic pathways.

Basic Information

Product Name	Rac Desisopropyl Tolterodine-D7
CAS No.	1346600-20-1
Molecular Formula	C21H24D7NO
Molecular Weight	310.5 g/mol (approx.)
Synonyms	2-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-methylphenol-d7; Desisopropyl Tolterodine-d7; Tolterodine Desisopropyl-d7; Tolterodine Impurity D7; Rac-Desisopropyl Tolterodine Deuterated; (R,S)-Desisopropyl Tolterodine-D7; N,N-Diisopropyl-3-phenyl-3-(2-hydroxy-5-methylphenyl)propylamine-d7; Deuterated Tolterodine Related Compound
EINECS	Contact for details

Quality Control

Our Rac Desisopropyl Tolterodine-D7 is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for chemical and isotopic purity, NMR for structural confirmation, and MS for identity verification. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with customer specifications for use in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC-MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98.0 atom % D
Chemical Purity	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.