Description

N,n-Dimethyl-3-Phenyl-1H-Indene-2-Ethanamine-D5 Hydrobromide is a deuterated hydrobromide salt of a complex indene-based amine, serving as a critical stable isotope-labeled compound for advanced research and development. This high-purity material is essential for applications requiring precise molecular tracking and quantification, such as in the development of analytical standards and metabolic studies. It is primarily utilized by pharmaceutical researchers, analytical chemists, and contract research organizations (CROs) engaged in drug discovery and development.

Application

• Internal Standard for LC-MS/MS: Used as a quantitative reference standard in bioanalytical method development for pharmacokinetic and metabolomic studies.
• Deuterated Reference Material: Serves as a critical standard in mass spectrometry to differentiate and quantify metabolites of non-labeled parent compounds.
• Pharmaceutical Research: Employed in drug discovery as a labeled analog for investigating the absorption, distribution, metabolism, and excretion (ADME) of lead compounds.
• Metabolic Pathway Tracing: Facilitates the detailed mapping of biochemical pathways in preclinical research.
• Quality Control & Method Validation: Provides a verified standard for validating analytical procedures in GLP/GMP-compliant laboratories.

Basic Information

Product Name	N,n-Dimethyl-3-Phenyl-1H-Indene-2-Ethanamine-D5 Hydrobromide
CAS No.	1346597-99-6
Molecular Formula	C19H16D5N•HBr
Molecular Weight	~357.3 g/mol
Synonyms	N,N-Dimethyl-3-phenyl-1H-indene-2-ethanamine-d5 hydrobromide; 2-[2-(Dimethylamino)ethyl]-3-phenyl-1H-indene-d5 hydrobromide; Deutetrabenazine Impurity D5 Hydrobromide; Tetrabenazine Metabolite D5 Hydrobromide; α-3-Phenyl-1H-indene-2-ethanamine, N,N-dimethyl-d5, hydrobromide; Deuterated Dihydrotetrabenazine Hydrobromide; (RS)-Dihydrotetrabenazine-d5 Hydrobromide; Deuterated HTBZ Hydrobromide
EINECS	Contact for details

Quality Control

Our N,n-Dimethyl-3-Phenyl-1H-Indene-2-Ethanamine-D5 Hydrobromide is manufactured under strict quality systems to ensure batch-to-batch consistency and high isotopic purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing results from advanced analytical techniques including NMR, HPLC, and mass spectrometry. We adhere to relevant industry standards for reference materials, and custom synthesis and purification to meet specific client specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content, MS)	≥ 98.0 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.