Description

1-Bromo-2-Isopropoxy-4-(Trifluoromethyl)Benzene is a high-purity, advanced pharmaceutical intermediate and versatile building block for complex organic synthesis. Its unique structure, featuring bromine and trifluoromethyl substituents, makes it a critical reagent for introducing specific functionalities into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Functional Material Development: Employed in creating novel polymers, ligands for catalysis, and specialty dyes with tailored properties.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry teams exploring new synthetic pathways and molecular scaffolds.

Basic Information

Item	Details
Product Name	1-Bromo-2-Isopropoxy-4-(Trifluoromethyl)Benzene
CAS No.	1345471-36-4
Molecular Formula	C10H10BrF3O
Molecular Weight	283.09 g/mol
Synonyms	2-Bromo-1-isopropoxy-4-(trifluoromethyl)benzene; 4-Bromo-3-isopropoxybenzotrifluoride; 1-Isopropoxy-2-bromo-4-(trifluoromethyl)benzene; 2-Isopropoxy-α,α,α-trifluoro-4-bromotoluene; 4-Bromo-α,α,α-trifluoro-3-isopropoxytoluene; 3-Isopropoxy-4-bromobenzotrifluoride
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Isopropoxy-4-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.