Description

6-Cyanopyridine-2-Sulfonyl Chloride is a versatile and highly reactive organic intermediate, primarily used as a key building block in advanced chemical synthesis. Its core value lies in its dual functional groups—the sulfonyl chloride and the nitrile—which enable efficient derivatization for creating complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of sulfonamide-based drug candidates, including kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require the pyridine-sulfonyl moiety for bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation and the development of activity-based probes (ABPs) targeting specific enzymes.
• Custom Synthesis & Contract Manufacturing: Employed by fine chemical companies for the bespoke production of complex molecules for client R&D projects.
• Ligand Development for Catalysis: Useful for constructing novel nitrogen-containing ligands used in homogeneous catalysis.

Basic Information

Product Name	6-Cyanopyridine-2-Sulfonyl Chloride
CAS No.	1343041-93-9
Molecular Formula	C6H3ClN2O2S
Molecular Weight	202.62 g/mol
Synonyms	2-Pyridinesulfonyl chloride, 6-cyano-; 6-Cyano-2-pyridinesulfonyl chloride; 6-Cyano-pyridine-2-sulfonyl chloride; 2-Cyanopyridine-6-sulfonyl chloride; 6-Cyanopyridine-2-sulfonylchloride; 2-Sulfonylchloride-6-cyanopyridine; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 6-Cyanopyridine-2-Sulfonyl Chloride is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.