Description

2-Ethyl-1H-Imidazole-4-Sulfonyl Chloride is a high-value, reactive sulfonyl chloride derivative of an imidazole heterocycle. This compound serves as a critical building block in advanced organic synthesis, enabling the introduction of the 2-ethylimidazole-4-sulfonyl moiety into target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for creating sulfonamide-based pharmacophores with targeted biological activity.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides where the imidazole-sulfonyl scaffold can confer specific modes of action.
• Material Science: Acts as a functionalization agent for polymers or surfaces, introducing imidazole groups that can alter material properties or enable further chemical modification.
• Chemical Biology Probe Synthesis: Employed in creating affinity probes or labeling reagents to study enzyme activity or protein interactions.
• Ligand and Catalyst Development: Serves as a starting point for synthesizing novel N-heterocyclic ligands used in coordination chemistry and catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific research projects and scale-up campaigns requiring this specialized intermediate.

Basic Information

Product Name	2-Ethyl-1H-Imidazole-4-Sulfonyl Chloride
CAS No.	1342111-54-9
Molecular Formula	C5H7ClN2O2S
Molecular Weight	194.64 g/mol
Synonyms	2-Ethyl-1H-imidazole-4-sulfonyl chloride; 2-Ethyl-1H-imidazole-4-sulfonchloride; 4-(Chlorosulfonyl)-2-ethyl-1H-imidazole; 2-Ethylimidazole-4-sulfonyl chloride; 1H-Imidazole-4-sulfonyl chloride, 2-ethyl-; 2-Ethyl-4-imidazolesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Ethyl-1H-Imidazole-4-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical range 95-98%)
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.