Description

Ethyl 2,2-Difluoro-2-(6-Methylpyridin-3-Yl)Acetate is a high-value fluorinated pyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a difluoroacetate ester and a methylpyridine moiety, makes it indispensable for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Research: Used in the development of next-generation pesticides and herbicides, where the difluoroacetate group can enhance biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or functionalization agent for creating specialty polymers and advanced materials with specific electronic or surface properties.
• Ligand Synthesis: Utilized in organometallic chemistry for the preparation of novel pyridine-based ligands used in catalysis.
• Fluorine Chemistry Research: An important reagent for studying the introduction and behavior of fluorine atoms in complex molecular architectures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical manufacturers for use in client-specific, multi-step synthetic routes.

Basic Information

Product Name	Ethyl 2,2-Difluoro-2-(6-Methylpyridin-3-Yl)Acetate
CAS No.	1341926-94-0
Molecular Formula	C10H11F2NO2
Molecular Weight	215.20 g/mol
Synonyms	Ethyl 2,2-Difluoro-2-(6-methyl-3-pyridinyl)acetate; 2,2-Difluoro-2-(6-methylpyridin-3-yl)acetic Acid Ethyl Ester; 3-Pyridineacetic acid, 2,2-difluoro-α-(6-methyl-3-pyridinyl)-, ethyl ester; Ethyl (6-Methylpyridin-3-yl)difluoroacetate; 1341926-94-0; Difluoro(6-methyl-3-pyridyl)acetic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 2,2-Difluoro-2-(6-Methylpyridin-3-Yl)Acetate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.