Description

3-Fluoro-4-(4-Methyl-1H-Pyrazol-1-Yl)Benzene-1-Sulfonyl Chloride is a high-value, multi-functional chemical building block designed for advanced synthetic applications. Its core value lies in the reactive sulfonyl chloride group, which enables efficient derivatization, and the unique fluorinated pyrazole heterocycle, offering opportunities for fine-tuning molecular properties. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate in the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrazole moiety.
• Material Science Research: Serves as a building block for creating specialized polymers, ligands, or metal-organic frameworks (MOFs) with tailored properties.
• Chemical Biology Probes: Employed in the development of activity-based probes or labeling reagents due to its reactive sulfonyl chloride handle.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring complex, fluorinated heterocyclic architectures.

Basic Information

Item	Details
Product Name	3-Fluoro-4-(4-Methyl-1H-Pyrazol-1-Yl)Benzene-1-Sulfonyl Chloride
CAS No.	1341340-38-2
Molecular Formula	C10H8ClFN2O2S
Molecular Weight	274.70 g/mol
Synonyms	1-(4-Chlorosulfonyl-2-fluorophenyl)-4-methyl-1H-pyrazole; 4-(4-Methyl-1H-pyrazol-1-yl)-3-fluorobenzenesulfonyl chloride; 3-Fluoro-4-(4-methylpyrazol-1-yl)benzenesulfonyl chloride; 2-Fluoro-4-(4-methyl-1H-pyrazol-1-yl)benzenesulfonyl chloride; 1-(2-Fluoro-4-(chlorosulfonyl)phenyl)-4-methyl-1H-pyrazole; 1341340-38-2; Fluoropyrazole sulfonyl chloride intermediate
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-4-(4-Methyl-1H-Pyrazol-1-Yl)Benzene-1-Sulfonyl Chloride is produced and tested under a strict quality management system. We ensure the product meets high-purity standards suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis and degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.