Description

1-Methyl-2-(Propan-2-Yl)-1H-Imidazole-4-Sulfonyl Chloride is a high-purity sulfonyl chloride derivative, a critical building block in modern organic synthesis. This compound matters for its exceptional reactivity as a sulfonylation reagent, enabling the efficient introduction of the sulfonyl functional group into target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of sulfonamide-based drug candidates, including protease inhibitors and kinase inhibitors.
• Agrochemical Synthesis: Used to create novel sulfonylurea or sulfonamide herbicides and fungicides with specific modes of action.
• Material Science: Building block for functional polymers and advanced materials requiring sulfonyl groups for specific electronic or solubility properties.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling proteins or modifying biomolecules in probe development.
• Custom Synthesis & Contract Manufacturing: Essential for research organizations and CDMOs developing proprietary compounds for clients.
• Scale-up Process Chemistry: Suitable for optimization and scaling from laboratory to pilot plant and commercial production.

Basic Information

Product Name	1-Methyl-2-(Propan-2-Yl)-1H-Imidazole-4-Sulfonyl Chloride
CAS No.	1340300-24-4
Molecular Formula	C7H11ClN2O2S
Molecular Weight	222.69 g/mol
Synonyms	2-Isopropyl-1-methyl-1H-imidazole-4-sulfonyl chloride; 1-Methyl-2-isopropylimidazole-4-sulfonyl chloride; 4-(Chlorosulfonyl)-1-methyl-2-(propan-2-yl)-1H-imidazole; 2-Isopropyl-1-methylimidazole-4-sulfonyl chloride; 1-Methyl-2-(1-methylethyl)-1H-imidazole-4-sulfonyl chloride; 4-(Chlorosulfonyl)-2-isopropyl-1-methylimidazole
EINECS	Contact for details

Quality Control

Our 1-Methyl-2-(Propan-2-Yl)-1H-Imidazole-4-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.