Description

6-Fluoro-2-Methoxy-3-Pyridinecarbonitrile is a high-value, multi-functional pyridine derivative serving as a critical building block in advanced organic synthesis. Its molecular architecture, featuring a fluorine atom, a methoxy group, and a nitrile functionality, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its electron-withdrawing nitrile group.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	6-Fluoro-2-Methoxy-3-Pyridinecarbonitrile
CAS No.	1339175-72-2
Molecular Formula	C7H5FN2O
Molecular Weight	152.13 g/mol
Synonyms	3-Cyano-6-fluoro-2-methoxypyridine; 2-Methoxy-6-fluoro-3-pyridinecarbonitrile; 6-Fluoro-2-methoxynicotinonitrile; 6-Fluoro-2-methoxy-3-cyanopyridine; 2-Methoxy-6-fluoronicotinonitrile; 6-Fluoro-2-methoxypyridine-3-carbonitrile; 3-Pyridinecarbonitrile, 6-fluoro-2-methoxy-
EINECS	Contact for details

Quality Control

Our 6-Fluoro-2-Methoxy-3-Pyridinecarbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.