Description

1-(6-Chlorophenyl-2,3,4,5-D4)-7-Oxabicyclo[4.1.0]Heptane is a deuterated analog of a key oxabicycloheptane intermediate, distinguished by its selective isotopic labeling. This compound is critical for advanced research and development, particularly in the fields of medicinal chemistry and analytical science, where it serves as a stable isotope-labeled internal standard. It is primarily utilized by pharmaceutical researchers, contract research organizations (CROs), and analytical laboratories requiring high-purity, well-characterized reference materials for method development and quantification.

Application

• As a stable isotope-labeled internal standard for the accurate quantification of its non-deuterated counterpart in complex matrices using LC-MS or GC-MS.
• In pharmacokinetic and metabolism studies (ADME) to trace and analyze drug candidate pathways within biological systems.
• For method development and validation in analytical laboratories to ensure precision, accuracy, and regulatory compliance.
• As a key advanced synthetic intermediate in the research and development of novel active pharmaceutical ingredients (APIs).
• In deuterium labeling studies to investigate chemical reaction mechanisms and metabolic stability.

Basic Information

Product Name	1-(6-Chlorophenyl-2,3,4,5-D4)-7-Oxabicyclo[4.1.0]Heptane
CAS No.	1336986-07-2
Molecular Formula	C12H9D4ClO
Molecular Weight	220.73 g/mol
Synonyms	1-(6-Chlorophenyl-d4)-7-oxabicyclo[4.1.0]heptane; 7-Oxabicyclo[4.1.0]heptane, 1-(6-chlorophenyl-2,3,4,5-d4)-; Deuterated 1-(6-Chlorophenyl)-7-oxabicyclo[4.1.0]heptane; 1-(6-Chloro-d4-phenyl)-7-oxabicyclo[4.1.0]heptane; 1-(6-Chlorophenyl)oxirane-d4 Cyclohexane Adduct; (6-Chlorophenyl-d4)oxirane Cyclohexane Adduct
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under strict quality control protocols to ensure high isotopic purity and chemical integrity. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and impurity profile is provided with every shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.