Description

Trpc6 Inhibitor CAS NO 1333207-63-8 is a potent and selective small molecule antagonist of the Transient Receptor Potential Canonical 6 (TRPC6) channel. This compound is a critical research tool for investigating calcium signaling pathways and their role in various physiological and pathological processes. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies focused on cardiovascular, renal, and neurological disease models.

Application

• Biomedical Research: Fundamental research into TRPC6 channel function, structure-activity relationships (SAR), and calcium influx mechanisms.
• Drug Discovery & Preclinical Studies: Used as a reference compound or pharmacological tool in high-throughput screening (HTS) and lead optimization programs targeting TRPC6.
• Cardiovascular Disease Models: Investigation of TRPC6's role in cardiac hypertrophy, pulmonary arterial hypertension, and vascular smooth muscle cell proliferation.
• Renal Physiology & Pathology: Study of podocyte function, glomerular diseases, and focal segmental glomerulosclerosis (FSGS).
• Neurological Research: Exploration of TRPC6 channels in neuroprotection, neuronal development, and conditions like stroke and epilepsy.
• Inflammatory Pathway Analysis: Research on the role of TRPC6 in immune cell signaling and inflammatory responses.

Basic Information

Item	Detail
Product Name	Trpc6 Inhibitor
CAS No.	1333207-63-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	TRPC6 Channel Blocker; TRPC6 Antagonist; (1R,2S)-2-Phenylcyclopropan-1-amine derivative (example IUPAC fragment); BI-749327 (example research code); SAR7334 (example research code); Compound 1333207-63-8; TRPC6 selective inhibitor
EINECS	Contact for details

Quality Control

Our Trpc6 Inhibitor is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS), to ensure identity, potency, and consistency for research applications. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, moisture-free environment. The product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, Ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.