Description

n-Acetyl-S-(2-Hydroxyethyl-D4)-L-Cysteine Dicyclohexylamine Salt is a deuterium-labeled derivative of a key mercapturic acid pathway metabolite. This compound matters for researchers and manufacturers requiring high-precision internal standards in quantitative bioanalytical methods, particularly for tracking exposure to specific xenobiotics. It is primarily needed by analytical laboratories, contract research organizations (CROs), and pharmaceutical companies engaged in advanced metabolomics, biomarker discovery, and toxicology studies where isotopic purity and structural fidelity are critical.

Application

• Primary use as a stable isotope-labeled internal standard for Liquid Chromatography-Mass Spectrometry (LC-MS/MS) quantification.
• Critical reagent in biomarker analysis for human exposure studies to ethylene oxide, acrylamide, and other industrial chemicals metabolized through the mercapturic acid pathway.
• Essential component in high-accuracy metabolomic research and pharmacokinetic studies requiring deuterium-labeled analogs.
• Used in the development and validation of regulatory-compliant analytical methods for occupational health and environmental monitoring.
• Reference material for quality control and assurance in clinical and forensic toxicology laboratories.
• Research chemical for studying glutathione conjugation pathways and related detoxification mechanisms.

Basic Information

Product Name	n-Acetyl-S-(2-Hydroxyethyl-D4)-L-Cysteine Dicyclohexylamine Salt
CAS No.	1331894-57-5
Molecular Formula	C17H30D4N2O4S
Molecular Weight	358.55 g/mol (for deuterated form)
Synonyms	N-Acetyl-S-(2-hydroxyethyl-1,1,2,2-d4)-L-cysteine dicyclohexylamine salt; Deuterated HEEMA-d4 DCHA salt; N-Acetyl-S-(2-hydroxyethyl-d4)cysteine dicyclohexylammonium salt; 2-[(Acetyl-D3-amino)-D]-3-[(2,2,2-trideuterio-1-hydroxyethyl)sulfanyl]propanoic acid dicyclohexylamine salt; HEEMA-d4 DCHA Salt; N-Acetyl-S-(2-hydroxyethyl-1,1,2,2-d4)cysteine dicyclohexylamine salt; Deuterated N-Acetyl-S-(2-hydroxyethyl)-L-cysteine DCHA salt-d4; Internal Standard for HEEMA Quantification
EINECS	Contact for details

Quality Control

Every batch of our n-Acetyl-S-(2-Hydroxyethyl-D4)-L-Cysteine Dicyclohexylamine Salt is produced and tested under strict quality management systems. We guarantee high isotopic purity and chemical identity critical for its use as a quantitative internal standard. Comprehensive analytical testing, including NMR, HPLC, and MS, is performed to confirm structure, isotopic enrichment (typically >98 atom % D), and chemical purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98 atom % D
Chemical Purity (Titration)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.