Description

n-Acetyl-S-[3-Acetamino-6-Hydroxphenyl]Cysteine-D5 Allyl Ester (Major) is a deuterated, acetylated cysteine derivative, serving as a crucial stable isotope-labeled intermediate. This compound is specifically designed for advanced research and development, offering high isotopic purity and structural integrity for precise analytical applications. It is primarily utilized by pharmaceutical researchers, analytical chemists, and contract research organizations (CROs) working on metabolite identification, pharmacokinetic studies, and the development of novel diagnostic agents.

Application

• Internal Standard for LC-MS/MS: Used as a quantitative reference standard in bioanalytical method development for drug metabolism and pharmacokinetics (DMPK) studies.
• Metabolite Synthesis & Identification: A key building block for the synthesis of deuterium-labeled drug metabolites to aid in structural elucidation and metabolic pathway mapping.
• Proteomics & Biomarker Research: Employed in the preparation of isotopically labeled peptides or protein conjugates for mass spectrometry-based quantitative proteomic analysis.
• Tracer Studies: Facilitates mechanistic studies in biochemistry and medicinal chemistry by tracing the incorporation and fate of specific molecular fragments.
• Pharmaceutical Reference Material: Serves as a certified reference material (CRM) or high-purity standard for quality control in drug development pipelines.

Basic Information

Product Name	n-Acetyl-S-[3-Acetamino-6-Hydroxphenyl]Cysteine-D5 Allyl Ester (Major)
CAS No.	1331889-45-2
Molecular Formula	C16H18D5N2O5S
Molecular Weight	Contact for details
Synonyms	N-Acetyl-S-(3-acetamido-6-hydroxyphenyl)-L-cysteine-d5 allyl ester; Deuterated Acetylcysteine Allyl Ester Derivative; 2-((Allyloxy)carbonyl)-2-(3-acetamido-6-hydroxyphenyl)sulfanyl-d5-ethanoic acid; S-[3-(Acetylamino)-6-hydroxyphenyl]-N-acetyl-D5-cysteine allyl ester; Stable Isotope Labeled Cysteine Metabolite; (2R)-2-Acetamido-3-[[3-acetamido-6-hydroxyphenyl]sulfanyl-d5]propanoic acid allyl ester
EINECS	Contact for details

Quality Control

Our n-Acetyl-S-[3-Acetamino-6-Hydroxphenyl]Cysteine-D5 Allyl Ester (Major) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for chemical and isotopic purity, NMR for structural confirmation, and mass spectrometry for identity verification. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and impurity profiles is provided with every shipment to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This material is hygroscopic (moisture-sensitive); allow the sealed container to equilibrate to room temperature before opening to prevent condensation. For short-term use (under one month), storage at 2-8°C is acceptable.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥95.0%
Isotopic Purity (D5)	≥98.0 atom % D
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.