Description

1-Benzylideneaminohydantoin-13C3 is a stable isotope-labeled derivative of the hydantoin core structure, specifically enriched with carbon-13 at three positions. This compound is of significant value as an internal standard and tracer in advanced analytical and metabolic research, ensuring precise quantification and reliable data integrity. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in drug metabolism and pharmacokinetics (DMPK) studies, proteomics, and biomarker discovery.

Application

• Used as an internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the accurate quantification of unlabeled 1-Benzylideneaminohydantoin and related analogs.
• Critical in drug metabolism studies (DMPK) to track the absorption, distribution, metabolism, and excretion (ADME) pathways of pharmaceutical compounds.
• Employed in proteomics and metabolomics research as a stable isotope-labeled tracer for pathway analysis and biomarker validation.
• Facilitates method development and validation in analytical chemistry, improving assay precision and reproducibility.
• Serves as a key building block or reference material in the synthesis of isotopically labeled complex molecules for research purposes.
• Applied in environmental fate studies to understand the degradation and transformation of chemical entities.

Basic Information

Product Name	1-Benzylideneaminohydantoin-13C3
CAS No.	1331666-40-0
Molecular Formula	C10H9N3O2 (with three 13C atoms)
Molecular Weight	~204.2 g/mol (Contact for exact isotopic weight)
Synonyms	(E)-2-(Benzylideneamino)-2,4-imidazolidinedione-13C3; 2-[(Phenylmethylene)amino]-2,4-imidazolidinedione-13C3; 1-Benzylideneaminohydantoin (13C3); Hydantoin, 1-(benzylideneamino)-, 13C3-labeled; Benzylideneaminohydantoin-13C3; Isotopically labeled hydantoin derivative; 13C3-1-Benzylideneaminohydantoin
EINECS	Contact for details

Quality Control

Every batch of 1-Benzylideneaminohydantoin-13C3 is manufactured and analyzed under strict quality protocols to ensure high isotopic and chemical purity, critical for research accuracy. Our quality assurance includes comprehensive testing via NMR, HPLC, and MS to verify isotopic enrichment, chemical identity, and purity. Certificates of Analysis (COA) detailing all specifications, including isotopic purity (atom % 13C), are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (13C NMR/MS)	≥ 99 atom % 13C (at three labeled positions)
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.