Description

Acetophenazine-D4 Dimaleate is a high-purity, deuterium-labeled internal standard critical for ensuring analytical accuracy and reliability in quantitative mass spectrometry. This stable isotope-labeled compound is essential for researchers and quality control laboratories requiring precise measurement and validation of the parent compound, Acetophenazine. It is primarily used in pharmaceutical research, forensic toxicology, and clinical diagnostics for method development and accurate quantification.

Application

• Internal Standard for LC-MS/MS: Used as a quantitative reference standard in liquid chromatography-tandem mass spectrometry for pharmacokinetic and bioanalytical studies.
• Pharmaceutical R&D: Enables precise metabolite profiling and drug metabolism studies in the development of phenothiazine-derived therapeutics.
• Forensic and Clinical Toxicology: Facilitates accurate screening and confirmation of Acetophenazine and related compounds in biological matrices.
• Method Validation and Compliance: Supports analytical method development, validation, and adherence to regulatory guidelines (e.g., FDA, EMA) in GLP/GMP environments.
• Isotope Dilution Mass Spectrometry (IDMS): Serves as the labeled spike in IDMS protocols for achieving the highest level of measurement certainty.
• Metabolomics Research: Aids in the identification and quantification of drug-related metabolites in complex biological systems.

Basic Information

Product Name	Acetophenazine-D4 Dimaleate
CAS No.	1331636-00-0
Molecular Formula	C23H22D4N2O2S • C4H4O4
Molecular Weight	Contact for details
Synonyms	Acetophenazine-d4 Dimaleate; 10-[3-(Dimethyl-d6-amino)propyl]phenothiazin-2-yl methyl ketone Dimaleate; Deuterated Acetophenazine Dimaleate; Acetophenazine (dimethyl-d6) Dimaleate; Acetophenazine-d4 Maleate Salt; 2-Acetyl-10-[3-(dimethyl-d6-amino)propyl]phenothiazine Dimaleate; Stable Isotope Labeled Acetophenazine Dimaleate
EINECS	Contact for details

Quality Control

Every batch of Acetophenazine-D4 Dimaleate is manufactured and tested under strict quality management systems to ensure exceptional isotopic purity and chemical integrity. Our products undergo rigorous quality testing, including advanced spectroscopic and chromatographic analyses, to ensure compliance with industry standards for stable isotope-labeled compounds. Certificates of Analysis (COA) detailing isotopic enrichment (typically >98% D), chemical purity (by HPLC), and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or Certificate of Analysis. This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (D-content)	≥98 atom % D
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.