Description

1,4-Dioxan-2-Ylmethanesulfonyl Chloride is a specialized sulfonyl chloride derivative, a key reactive intermediate in advanced organic synthesis. Its value lies in its ability to act as a versatile sulfonylation reagent, facilitating the introduction of the methanesulfonyl (mesyl) group into complex molecular architectures under controlled conditions. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of sulfonamide-based drug candidates and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific sulfonyl functionalities.
• Chemical Research & Development: Serves as a versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating complex organic molecules.
• Material Science: Potential applications in the synthesis of specialty polymers and functional materials where sulfonyl groups modify material properties.
• Process Chemistry: Employed in scale-up and optimization studies for the efficient production of target molecules in pilot and commercial-scale manufacturing.

Basic Information

Product Name	1,4-Dioxan-2-Ylmethanesulfonyl Chloride
CAS No.	1330756-16-5
Molecular Formula	C6H9ClO4S
Molecular Weight	212.65 g/mol
Synonyms	2-(Chlorosulfonyl)methyl-1,4-dioxane; 1,4-Dioxan-2-ylmethanesulfonyl chloride; 2-(Methanesulfonyl chloride)-1,4-dioxane; (1,4-Dioxan-2-yl)methanesulfonyl chloride; 2-(Chlorosulfonylmethyl)-1,4-dioxane; Dioxanylmesyl chloride; 1,4-Dioxane-2-methanesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 1,4-Dioxan-2-Ylmethanesulfonyl Chloride is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area%)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.