Description

Vardenafil Acetyl-D5 Analogue is a deuterated internal standard critical for precise quantitative analysis in pharmaceutical research and development. This high-purity compound is specifically designed for use in Liquid Chromatography-Mass Spectrometry (LC-MS) and other advanced analytical techniques, ensuring accurate and reliable measurement of the parent drug, Vardenafil. It is an essential tool for scientists and quality control professionals in pharmaceutical manufacturing, contract research organizations (CROs), and analytical laboratories focused on method development, pharmacokinetic studies, and impurity profiling.

Application

• Primary use as a deuterated internal standard (IS) for the quantification of Vardenafil in biological matrices (e.g., plasma, serum) using LC-MS/MS.
• Method development and validation for bioanalytical assays in clinical and preclinical pharmacokinetic/pharmacodynamic (PK/PD) studies.
• Quality control and stability testing of Vardenafil active pharmaceutical ingredient (API) and finished dosage forms.
• Metabolite identification and impurity profiling studies in pharmaceutical R&D.
• Use in forensic and anti-doping analysis for the accurate detection and quantification of Vardenafil and related substances.
• Supporting regulatory submissions by providing validated analytical methods with high specificity and accuracy.

Basic Information

Product Name	Vardenafil Acetyl-D5 Analogue
CAS No.	1330171-51-1
Molecular Formula	C23H27D5N6O4S
Molecular Weight	~ 492.61 g/mol
Synonyms	Vardenafil-d5; Vardenafil Deuterated Standard; 2-[2-Ethoxy-5-[(4-ethylpiperazin-1-yl)sulfonyl]phenyl]-5-methyl-7-propyl-1H-imidazo[5,1-f][1,2,4]triazin-4(3H)-one-d5; Vardenafil (Acetyl-d5); Vardenafil Internal Standard-d5; Levitra-d5 (Analogue); N-[2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl]-5-methyl-7-propyl-1H-imidazo[5,1-f][1,2,4]triazin-4(3H)-one-d5
EINECS	Contact for details

Quality Control

Every batch of our Vardenafil Acetyl-D5 Analogue is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We guarantee high chemical and isotopic purity to meet the exacting requirements of analytical reference standards. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results for assay, isotopic enrichment, and impurity profiles as determined by HPLC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.