Description

1,4-Bis(1-Aziridinyl)-2,3-Butanedione-D8 Dihydrobromide is a deuterated derivative of a bifunctional aziridine compound, serving as a specialized cross-linking agent and building block in advanced chemical synthesis. This high-purity, isotopically labeled compound is critical for research and development requiring precise molecular tracking and mechanistic studies. It is primarily utilized by pharmaceutical researchers, agrochemical developers, and advanced materials scientists working on novel polymers and targeted drug delivery systems.

Application

• Pharmaceutical Research: Used as a deuterium-labeled intermediate in the synthesis of novel active pharmaceutical ingredients (APIs) for metabolism and pharmacokinetic (DMPK) studies.
• Polymer Science: Acts as a cross-linking agent in the development of specialty polymers, coatings, and resins, where its aziridine groups enable ring-opening polymerization.
• Agrochemical Development: Employed in the synthesis of labeled agrochemicals for environmental fate and degradation pathway analysis.
• Bioconjugation: Serves as a linker molecule for attaching functional groups or probes to biomolecules in diagnostic assay development.
• Material Science: Utilized in surface modification and the creation of functionalized nanomaterials with specific chemical properties.
• Analytical Standards: Provides an internal standard for quantitative mass spectrometry (LC-MS, GC-MS) analysis in complex matrices.

Basic Information

Product Name	1,4-Bis(1-Aziridinyl)-2,3-Butanedione-D8 Dihydrobromide
CAS No.	1329485-50-8
Molecular Formula	C8D8H6Br2N2O2
Molecular Weight	Contact for details
Synonyms	1,4-Bis(aziridin-1-yl)-2,3-butanedione-D8 dihydrobromide; 2,3-Butanedione-D8, 1,4-bis(1-aziridinyl)-, dihydrobromide; Deuterated BAD dihydrobromide; BAD-D8 Dihydrobromide; 1,4-Diaziridinyl-2,3-butanedione-D8 Dihydrobromide; Aziridine cross-linker-D8 salt; Isotopically labeled aziridine derivative
EINECS	Contact for details

Quality Control

Our 1,4-Bis(1-Aziridinyl)-2,3-Butanedione-D8 Dihydrobromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and isotopic enrichment meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing specifications such as isotopic purity (D-enrichment), chemical purity (by HPLC), and residual solvent content is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.