Description

S1P1 Agonist Iii is a potent and selective small molecule agonist targeting the sphingosine-1-phosphate receptor 1 (S1P1). This compound is a critical research tool for studying S1P1 receptor signaling pathways, which are involved in immune cell trafficking, vascular function, and inflammatory responses. It is essential for pharmaceutical R&D, academic research, and preclinical development programs focused on immunology, autoimmune diseases, and cardiovascular research. The product is supplied with high purity and batch-to-batch consistency to ensure reliable experimental results.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies investigating S1P1 receptor biology, activation kinetics, and downstream signaling.
• Drug Discovery & Development: Serves as a lead compound or tool molecule for screening, validating assays, and developing novel therapeutics targeting the S1P pathway.
• Immunology & Autoimmune Disease Models: Applied in in vitro and in vivo models to modulate lymphocyte egress and study potential treatments for conditions like multiple sclerosis and psoriasis.
• Cardiovascular Research: Utilized to explore the role of S1P1 in endothelial barrier function, vascular maturation, and angiogenesis.
• Biochemical Assay Development: Acts as a key component in establishing high-throughput screening (HTS) platforms and functional cellular assays for S1P1 receptor activity.

Basic Information

Product Name	S1P1 Agonist Iii
CAS No.	1324003-64-6
Molecular Formula	C₂₉H₃₀N₄O₃
Molecular Weight	482.58 g/mol
Synonyms	CS-2100; BAF-312 analog; Siponimod related compound; 2-[(2S)-2-Amino-3-[3,4-bis(phenylmethoxy)phenyl]propyl]-2-(2-methylpropyl)-1H-isoindole-1,3(2H)-dione; S1P1 receptor modulator III; S1PR1 agonist; Immunomodulator research compound
EINECS	Contact for details

Quality Control

Every batch of S1P1 Agonist Iii is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and potency. Our quality commitment includes comprehensive characterization by HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.