Description

n-(2-Hydroxyethyl)-1-Deoxygalactonojirimycin Hydrochloride is a high-purity synthetic iminosugar derivative, specifically a galactose analog. This compound is a critical pharmacological research tool and a key intermediate in the development of glycosidase inhibitors. It is primarily sought by pharmaceutical R&D and academic research institutions focused on metabolic disorders, lysosomal storage diseases, and antiviral therapies.

Application

• Pharmaceutical Research & Development: As a potent and selective inhibitor of α-galactosidase and other glycosidases for target validation and mechanism-of-action studies.
• Preclinical Drug Candidate: Serves as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel therapeutics for Fabry disease and related disorders.
• Biochemical Assay Standard: Used as a reference standard in enzymatic assays to study carbohydrate metabolism and enzyme kinetics.
• Chemical Biology Probes: Employed in the development of activity-based probes to profile glycosidase activities in complex biological systems.
• Academic Research: Fundamental research into glycosphingolipid metabolism, protein folding disorders, and the role of glycosidases in cellular pathways.

Basic Information

Product Name	n-(2-Hydroxyethyl)-1-Deoxygalactonojirimycin Hydrochloride
CAS No.	1322625-07-9
Molecular Formula	C8H16N2O5 • HCl
Molecular Weight	256.68 g/mol (Free base: 220.22 g/mol)
Synonyms	1-Deoxygalactonojirimycin N-2-Hydroxyethyl Hydrochloride; N-Hydroxyethyl-DGJ HCl; N-(2-Hydroxyethyl)-1,5-dideoxy-1,5-imino-D-galactitol Hydrochloride; Migalastat Impurity; AT2220 (Hydrochloride Salt); Galactose Mimetic Inhibitor; α-Galactosidase Inhibitor Derivative; Iminosugar Hydrochloride Salt
EINECS	Contact for details

Quality Control

Every batch of n-(2-Hydroxyethyl)-1-Deoxygalactonojirimycin Hydrochloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to support research and regulatory filings, including HPLC purity, chiral purity, and identity confirmation via NMR and MS. A detailed Certificate of Analysis (COA) is supplied with each shipment, ensuring traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.