Description

5-Fluoro-2-Methoxypyridine-4-Boronic Acid Pinacol Ester is a high-purity, synthetically valuable boronic ester derivative, essential for modern cross-coupling reactions. Its core value lies in enabling the precise construction of complex heterocyclic scaffolds, which are critical in advanced material and pharmaceutical research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-couplings for synthesizing fluorinated pyridine derivatives with potential biological activity.
• Agrochemical Research: Used to create novel herbicide and pesticide candidates by introducing the 5-fluoro-2-methoxypyridine moiety into target molecules.
• Material Science: Serves as a precursor for constructing organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Synthesis: Enables the efficient, palladium-catalyzed formation of carbon-carbon bonds in complex molecule assembly.
• Library Synthesis: Ideal for generating diverse compound libraries in drug discovery programs for high-throughput screening.
• Process Chemistry: Employed in the scale-up and optimization of routes to active pharmaceutical ingredients (APIs).

Basic Information

Product Name	5-Fluoro-2-Methoxypyridine-4-Boronic Acid Pinacol Ester
CAS No.	1315351-46-2
Molecular Formula	C₁₂H₁₇BFNO₃
Molecular Weight	253.08 g/mol
Synonyms	4,4,5,5-Tetramethyl-2-(5-fluoro-2-methoxypyridin-4-yl)-1,3,2-dioxaborolane; (5-Fluoro-2-methoxypyridin-4-yl)boronic acid pinacol ester; 5-Fluoro-2-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-(5-Fluoro-2-methoxypyridin-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Fluoro-2-methoxy-4-pyridineboronic acid pinacol ester; 1315351-46-2; Boronic acid, B-(5-fluoro-2-methoxy-4-pyridinyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Methoxypyridine-4-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided to guarantee consistency and reliability for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.