Description

5-(4-Fluoro-3-Methoxyphenyl)Pyridin-2-Amine is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both a fluorine atom and a methoxy group on the phenyl ring, makes it a valuable scaffold for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor research and central nervous system (CNS) targeted therapies.
• Agrochemical Research: Used to develop new herbicides and fungicides, where the fluorine moiety can enhance biological activity and environmental stability.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals for electronic displays.
• Chemical Synthesis: Acts as a versatile aryl amine coupling partner in cross-coupling reactions (e.g., Buchwald-Hartwig amination) for constructing biaryl systems.
• Life Science Reagents: Employed in the development of fluorescent probes, biochemical sensors, and other diagnostic tools.

Basic Information

Product Name	5-(4-Fluoro-3-Methoxyphenyl)Pyridin-2-Amine
CAS No.	1314988-51-6
Molecular Formula	C12H11FN2O
Molecular Weight	218.23 g/mol
Synonyms	2-Amino-5-(4-fluoro-3-methoxyphenyl)pyridine; 5-(4-Fluoro-3-methoxyphenyl)-2-pyridinamine; 2-Pyridinamine, 5-(4-fluoro-3-methoxyphenyl)-; 1314988-51-6; 5-(4-Fluoro-3-methoxyphenyl)pyridin-2-ylamine; 4-Fluoro-3-methoxy-[1,1'-biphenyl]-2-amine (related); 5-(4-Fluoro-3-methoxyphenyl)-2-aminopyridine
EINECS	Contact for details

Quality Control

Our 5-(4-Fluoro-3-Methoxyphenyl)Pyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.