Description

2-Methyl-1,3-Thiazole-5-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative, a critical building block in modern synthetic chemistry. Its primary value lies in its role as a versatile sulfonylation reagent, enabling the efficient introduction of the 2-methylthiazole-5-sulfonyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the thiazole sulfonamide structure imparts specific biological activity.
• Chemical Biology Probe Development: Employed to create sulfonamide-based probes and affinity labels for studying protein function and interactions.
• Material Science Research: Serves as a precursor for functionalized polymers or specialty chemicals with tailored surface properties.
• Custom Synthesis & Contract Manufacturing: A vital reagent for fine chemical and CDMO (Contract Development and Manufacturing Organization) facilities producing bespoke molecules for clients.

Basic Information

Product Name	2-Methyl-1,3-Thiazole-5-Sulfonyl Chloride
CAS No.	1314977-63-3
Molecular Formula	C4H4ClNO2S2
Molecular Weight	197.66 g/mol
Synonyms	5-(Chlorosulfonyl)-2-methyl-1,3-thiazole; 2-Methylthiazole-5-sulfonyl chloride; 2-Methyl-5-thiazolesulfonyl chloride; 1,3-Thiazole-5-sulfonyl chloride, 2-methyl-; 2-Methyl-1,3-thiazol-5-ylsulfonyl chloride; 5-Chlorosulfonyl-2-methylthiazole
EINECS	Contact for details

Quality Control

Every batch of 2-Methyl-1,3-Thiazole-5-Sulfonyl Chloride is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality protocols are designed to support cGMP (current Good Manufacturing Practice) compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.