Description

4-Fluoro-2-Methyl-1-(Methylsulfanyl)Benzene is a high-purity fluorinated aromatic building block featuring a methylthio substituent, which is critical for introducing sulfur-based functionality into advanced molecular architectures. This compound matters for its role as a versatile intermediate in the synthesis of complex agrochemicals, pharmaceuticals, and specialty materials, where precise control over molecular structure is paramount. It is needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers for advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized to create fluorinated and thioether-containing molecular probes for studying enzyme mechanisms and protein interactions.

Basic Information

Product Name	4-Fluoro-2-Methyl-1-(Methylsulfanyl)Benzene
CAS No.	1314931-17-3
Molecular Formula	C8H9FS
Molecular Weight	156.22 g/mol
Synonyms	1-Fluoro-2-methyl-4-(methylthio)benzene; 4-Fluoro-2-methylthioanisole; 2-Methyl-4-fluoro-1-(methylsulfanyl)benzene; 4-Fluoro-o-tolyl methyl sulfide; (4-Fluoro-2-methylphenyl)(methyl)sulfane; Methyl 4-fluoro-2-methylphenyl sulfide
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Methyl-1-(Methylsulfanyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.