Description

tert-Butyl (6-Fluoropyridin-3-Yl)Methylcarbamate (Wx191682) is a high-purity, advanced pharmaceutical intermediate featuring a fluorinated pyridine core and a Boc-protected amine group. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to introduce fluorinated pyridine motifs.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced pesticides and herbicides containing fluorinated heterocycles.
• Peptide Mimetics & PROTACs: The Boc-protected amine is valuable for constructing peptide-like molecules and proteolysis-targeting chimeras (PROTACs).
• Chemical Biology Probes: Employed in the creation of fluorinated probes for studying enzyme mechanisms and biological pathways.
• Scale-up Process Development: Suitable for process optimization and pilot-scale production under current Good Manufacturing Practices (cGMP) for clinical trial material supply.

Basic Information

Product Name	tert-Butyl (6-Fluoropyridin-3-Yl)Methylcarbamate (Wx191682)
CAS No.	1314538-84-5
Molecular Formula	C11H15FN2O2
Molecular Weight	226.25 g/mol
Synonyms	tert-Butyl N-[(6-fluoropyridin-3-yl)methyl]carbamate; Carbamic acid, N-[(6-fluoro-3-pyridinyl)methyl]-, 1,1-dimethylethyl ester; 3-Pyridinemethanamine, 6-fluoro-, N-BOC-protected; BOC-6-Fluoro-3-pyridylmethylamine; (6-Fluoropyridin-3-yl)methylcarbamic acid tert-butyl ester; Wx191682; tert-Butyl (6-fluoro-3-pyridylmethyl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl (6-Fluoropyridin-3-Yl)Methylcarbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting regulatory filings and cGMP compliance for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.