Description

7,8-Difluoro-3-Iodoquinoline is a high-value halogenated quinoline derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antimicrobial research.
• Agrochemical Synthesis: Used to create advanced herbicides, fungicides, and pesticides by introducing the difluoroquinoline scaffold.
• Material Science Research: Building block for organic semiconductors, liquid crystals, and photoactive materials due to its electron-deficient quinoline core.
• Cross-Coupling Reactions: The iodine atom serves as an excellent handle for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig couplings.
• Fluorinated Compound Libraries: Essential for medicinal chemistry programs focused on exploring the benefits of fluorination in lead optimization.
• Chemical Biology Probes: Used to develop fluorescent tags or affinity probes for studying biological systems.

Basic Information

Product Name	7,8-Difluoro-3-Iodoquinoline
CAS No.	1314012-54-8
Molecular Formula	C9H4F2IN
Molecular Weight	306.04 g/mol
Synonyms	3-Iodo-7,8-difluoroquinoline; 7,8-Difluoro-3-iodoquinoline; Quinoline, 7,8-difluoro-3-iodo-; 1314012-54-8; 7,8-Difluoro-3-iodo-quinoline
EINECS	Contact for details

Quality Control

Our 7,8-Difluoro-3-Iodoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and reliability for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.