Description

Akt Inhibitor 2 CAS NO 1313881-70-7 is a potent and selective small molecule inhibitor of the Akt (Protein Kinase B) signaling pathway, a critical regulator of cell survival, growth, and metabolism. This compound is essential for researchers and developers in the life sciences sector, providing a reliable tool for investigating oncogenesis, metabolic disorders, and cellular resistance mechanisms. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on targeted cancer therapy and signal transduction studies.

Application

• Biomedical Research: A key reagent for in vitro and in vivo studies of the PI3K/Akt/mTOR signaling pathway in cancer biology.
• Drug Discovery & Development: Used as a reference standard and pharmacological tool compound in high-throughput screening and lead optimization for oncology targets.
• Mechanistic Studies: Enables investigation of cellular processes such as apoptosis, proliferation, and glucose metabolism by selectively inhibiting Akt isoforms.
• Preclinical Research: Employed in animal models to evaluate the therapeutic potential of Akt pathway inhibition for treating various malignancies.
• Biochemical Assay Development: Serves as a critical control in developing and validating kinase inhibition assays and diagnostic tests.

Basic Information

Item	Detail
Product Name	Akt Inhibitor 2
CAS No.	1313881-70-7
Molecular Formula	C₂₀H₂₀N₆O₂S
Molecular Weight	408.48 g/mol
Synonyms	AKT Inhibitor 2; Akti-2; Akt inhibitor 2; 8-(1H-Indazol-5-yl)-2-((2-(trifluoromethyl)benzyl)thio)pyrido[2,3-d]pyrimidin-7(8H)-one; 8-(1H-Indazol-5-yl)-2-[[[2-(trifluoromethyl)phenyl]methyl]thio]pyrido[2,3-d]pyrimidin-7-one; Pyrido[2,3-d]pyrimidin-7(8H)-one, 8-(1H-indazol-5-yl)-2-[[[2-(trifluoromethyl)phenyl]methyl]thio]-
EINECS	Contact for details

Quality Control

Our Akt Inhibitor 2 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals, and specifications can be provided to meet the stringent requirements of pharmaceutical R&D and academic research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.