Description

9H-Pyrrolo[2,3-B:5,4-C']Dipyridine-6-Carbonitrile, 3-Fluoro-5-Hydroxy-9-(Phenylsulfonyl)- is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of novel small-molecule therapeutics. It is primarily sought after by R&D teams and process chemists in the pharmaceutical and biotechnology sectors for constructing targeted drug candidates.

Application

This specialized intermediate serves as a critical building block in several high-value research and development applications:

• Pharmaceutical Intermediate: Core scaffold for the synthesis of potential kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Key starting material for structure-activity relationship (SAR) studies and lead optimization programs.
• Process Development: Used in scaling up synthetic routes for preclinical and clinical trial material production.
• Chemical Biology Probes: Serves as a precursor for developing tool compounds to study biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis for drug discovery clients.

Basic Information

Product Name	9H-Pyrrolo[2,3-B:5,4-C']Dipyridine-6-Carbonitrile, 3-Fluoro-5-Hydroxy-9-(Phenylsulfonyl)-
CAS No.	1312755-45-5
Molecular Formula	C₁₈H₁₀FN₃O₃S
Molecular Weight	367.36 g/mol
Synonyms	3-Fluoro-5-hydroxy-9-(phenylsulfonyl)-9H-pyrrolo[2,3-b:5,4-c']dipyridine-6-carbonitrile; 9H-Pyrrolo[2,3-b:5,4-c']dipyridine-6-carbonitrile, 3-fluoro-5-hydroxy-9-(phenylsulfonyl)-; 1312755-45-5; 3-Fluoro-5-hydroxy-9-(benzenesulfonyl)-9H-pyrrolo[2,3-b:5,4-c']dipyridine-6-carbonitrile
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and reliability for critical research applications. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and MS. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.