Description

Ethyl 1-(5-Fluoropyridin-2-Yl)Piperidine-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS number 1310820-59-7. This compound is a critical building block in modern medicinal chemistry, valued for its piperidine-carboxylate core and fluoropyridine moiety, which are essential for modulating the biological activity and pharmacokinetic properties of target molecules. It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas such as central nervous system (CNS) disorders and oncology.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• CNS Drug Development: Used in the research and synthesis of potential therapeutics targeting neurological and psychiatric conditions.
• Oncology Research: Employed as a building block for developing small-molecule inhibitors and targeted cancer therapies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for exploratory organic synthesis and pharmacological studies.

Basic Information

Product Name	Ethyl 1-(5-Fluoropyridin-2-Yl)Piperidine-4-Carboxylate
CAS No.	1310820-59-7
Molecular Formula	C13H17FN2O2
Molecular Weight	252.29 g/mol
Synonyms	Ethyl 1-(5-Fluoropyridin-2-yl)piperidine-4-carboxylate; 1-(5-Fluoropyridin-2-yl)piperidine-4-carboxylic Acid Ethyl Ester; Ethyl 1-(5-Fluoro-2-pyridinyl)-4-piperidinecarboxylate; 4-Piperidinecarboxylic acid, 1-(5-fluoro-2-pyridinyl)-, ethyl ester; 1310820-59-7; UNII-7G8J2Q8K4W; 7G8J2Q8K4W; SCHEMBL21826527
EINECS	Contact for details

Quality Control

Our Ethyl 1-(5-Fluoropyridin-2-Yl)Piperidine-4-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects with material suitable for research use and can supply material produced under current Good Manufacturing Practice (cGMP) guidelines for advanced clinical trials upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and may require storage under an inert atmosphere for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.