Description

3-Fluoropyridin-2-Yl Trifluoromethanesulfonate is a high-value triflate ester building block used in advanced organic synthesis. This compound is critical for introducing the 3-fluoro-2-pyridyl moiety into target molecules via cross-coupling reactions, enabling the development of novel chemical entities. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki, Stille, and Negishi cross-coupling reactions for constructing biaryl systems found in drug candidates.
• Agrochemical Synthesis: Used to incorporate fluorinated pyridine motifs into novel herbicides, fungicides, and insecticides to enhance biological activity and environmental stability.
• Ligand Precursor: Serves as a starting material for the synthesis of specialized nitrogen-containing ligands used in catalysis.
• Material Science Research: Employed in the development of organic electronic materials and fluorinated liquid crystals.
• Chemical Biology Probes: Useful for creating fluorinated analogs of bioactive molecules for metabolic and binding studies.

Basic Information

Product Name	3-Fluoropyridin-2-Yl Trifluoromethanesulfonate
CAS No.	1310559-92-2
Molecular Formula	C7H3F4NO3S
Molecular Weight	257.16 g/mol
Synonyms	2-(Trifluoromethanesulfonyloxy)-3-fluoropyridine; 3-Fluoro-2-pyridyl triflate; 3-Fluoro-2-pyridinyl trifluoromethanesulfonate; 3-Fluoropyridin-2-yl triflate; 2-Pyridinol, 3-fluoro-, 1,1,1-trifluoromethanesulfonate (ester); Trifluoromethanesulfonic acid 3-fluoro-2-pyridinyl ester; 3-Fluoro-2-trifluoromethanesulfonyloxypyridine
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoropyridin-2-Yl Trifluoromethanesulfonate is manufactured and tested under strict quality management systems. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.