Description

6-Trifluoroacetylpyridine-3-Boronic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its core value lies in enabling the efficient construction of complex molecular architectures through reliable cross-coupling reactions. This advanced intermediate is primarily needed by R&D and production teams in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products, leveraging the stability of the trifluoroacetyl and boronic acid groups.
• Ligand & Catalyst Development: Serves as a building block for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials and metal-organic frameworks (MOFs) due to its ability to form stable covalent bonds.
• Chemical Biology Probes: Utilized in the development of molecular probes and sensors for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the fine chemical and life science sectors.

Basic Information

Product Name	6-Trifluoroacetylpyridine-3-Boronic Acid
CAS No.	1310384-03-2
Molecular Formula	C7H5BF3NO3
Molecular Weight	218.93 g/mol
Synonyms	3-Borono-6-(trifluoroacetyl)pyridine; (6-(Trifluoroacetyl)pyridin-3-yl)boronic acid; 6-(Trifluoroacetyl)-3-pyridineboronic acid; 5-Borono-2-(trifluoroacetyl)pyridine; 2-Pyridineboronic acid, 6-(trifluoroacetyl)-; 1310384-03-2; 6-Trifluoroacetyl-3-pyridylboronic acid
EINECS	Contact for details

Quality Control

Our 6-Trifluoroacetylpyridine-3-Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.