Description

3-Fluoropyridine-2-Boronic Acid Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. This compound matters as a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. Pharmaceutical, agrochemical, and advanced materials researchers need it for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing fluorinated pyridine derivatives with potential biological activity.
• Agrochemical Synthesis: Used in the research and development of new crop protection agents and herbicides.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boron reagent for palladium-catalyzed carbon-carbon bond formation to create complex aromatic systems.
• Material Science Research: Employed in the synthesis of organic electronic materials, ligands for catalysis, and novel polymers.
• Chemical Biology Probes: Useful for creating fluorinated molecular probes and tags for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke chemical synthesis projects.

Basic Information

Product Name	3-Fluoropyridine-2-Boronic Acid Pinacol Ester
CAS No.	1309982-68-0
Molecular Formula	C11H15BFNO2
Molecular Weight	223.05 g/mol
Synonyms	2-(3-Fluoropyridin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (3-Fluoropyridin-2-yl)boronic acid pinacol ester; 3-Fluoro-2-pyridineboronic acid pinacol ester; 3-Fluoropyridine-2-boronic acid neopentyl glycol ester (common alternative); 3-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-fluoropyridine; 3-Fluoro-2-pyridylboronic acid pinacol ester; B-(3-Fluoropyridin-2-yl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 3-Fluoropyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistency for sensitive synthetic applications. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.