Description

2-Fluoro-6-(Pyrrolidin-1-Yl)-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value, multi-functional organoboron building block designed for advanced chemical synthesis. This compound matters because it provides a protected boronic ester group, enabling efficient cross-coupling reactions critical for constructing complex molecular architectures. Pharmaceutical, agrochemical, and advanced materials researchers need it as a key intermediate for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic ester reagent for forming carbon-carbon bonds, a fundamental step in medicinal and process chemistry.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the fluorine and heterocyclic motifs for bioactivity.
• Material Science: A precursor for creating organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and labeled compounds for biochemical assays and diagnostic research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects requiring specific fluorinated pyridine derivatives.

Basic Information

Item	Details
Product Name	2-Fluoro-6-(Pyrrolidin-1-Yl)-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1309978-63-9
Molecular Formula	C15H22BFN2O2
Molecular Weight	292.16 g/mol
Synonyms	2-Fluoro-6-(1-pyrrolidinyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-Boronic acid, 2-fluoro-6-(1-pyrrolidinyl)pyridine-, 1,3,2-dioxaborolane ester; 2-Fluoro-6-pyrrolidin-1-yl-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridine; 1309978-63-9; Pinacol 2-fluoro-6-(pyrrolidin-1-yl)pyridin-3-ylboronate
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-(Pyrrolidin-1-Yl)-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.